| Pair Name | Flavokawain B, Daunorubicin | ||
| Phytochemical Name | Flavokawain B (PubChem CID: 5356121 ) | ||
| Anticancer drug Name | Daunorubicin (PubChem CID: 30323 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Flavokawain B, Daunorubicin | |||
| Disease Info | [ICD-11: 2B33.4] | Leukemia | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Activity | NFKB1 | hsa4790 |
| In Vitro Model | HL-60 | Adult acute myeloid leukemia | Homo sapiens (Human) | CVCL_0002 |
| K-562 | Blast phase chronic myelogenous leukemia | Homo sapiens (Human) | CVCL_0004 | |
| MOLT-4 | Adult T acute lymphoblastic leukemia | Homo sapiens (Human) | CVCL_0013 | |
| Result | A combination treatment of DNR and FKB may improve the anticancer effects of DNR in DNR-resistant acute myeloid leukemia. | |||
| No. | Title | Href |
|---|---|---|
| 1 | The Combination of Flavokawain B and Daunorubicin Induces Apoptosis in Human Myeloid Leukemic Cells by Modifying NF-κB. Anticancer Res. 2018 May;38(5):2771-2778. doi: 10.21873/anticanres.12520. | Click |
